Title : 2 Changes In Glomerular Parietal Epithelial Cells In Mouse Kidneys With Advanced Age
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چکیده
1 1 Title: 2 Changes In Glomerular Parietal Epithelial Cells In Mouse Kidneys With Advanced Age 3 4 Authors: 5 Sebastian S. Roeder, Ania Stefanska, Diana G. Eng, Natalya Kaverina, Maria W. Sunseri, 6 Bairbre A. McNicholas, Peter Rabinovitch, Felix B. Engel, Christoph Daniel, Kerstin 7 Amann, Julia Lichtnekert, Jeffrey W. Pippin, Stuart J. Shankland 8 9 Institutions: 10 1) Division of Nephrology, University of Washington, Seattle, WA, USA 11 2) Department of Pathology, University of Washington, Seattle, WA, USA 12 3) Department of Nephropathology, Friedrich-Alexander-Universität Erlangen-Nürnberg 13 (FAU), Erlangen, Germany 14 4) Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany 15 16 COI: None of the authors have any financial or other conflicts of interest. The results presented 17 in this paper have not been published previously, in whole or part. 18 19 Number of pages: 42 20 Word Count: 6240 21 Tables: 0 22 Figures: 11 23 24 Short Running Head: PECs and Aging 25 26 Corresponding Author: Stuart J Shankland, Division of Nephrology, Department of Medicine, 27 University of Washington School of Medicine, Box 358058, 750 Republican Street, Seattle, WA 28 98109. Phone: (206) 543-2346; Fax: (206) 685-8661; E-mail: [email protected] 29 30 Articles in PresS. Am J Physiol Renal Physiol (June 3, 2015). doi:10.1152/ajprenal.00144.2015
منابع مشابه
Changes in glomerular parietal epithelial cells in mouse kidneys with advanced age.
Kidney aging is accompanied by characteristic changes in the glomerulus, but little is known about the effect of aging on glomerular parietal epithelial cells (PECs), nor if the characteristic glomerular changes in humans and rats also occur in very old mice. Accordingly, a descriptive analysis was undertaken in 27-mo-old C57B6 mice, considered advanced age. PEC density was significantly lower ...
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